Dura mater
Dura mater
Also known as: pachymeninx, dura
The thick, tough outermost meninx; in the skull it has periosteal and meningeal layers that separate to enclose the dural venous sinuses and fold inwards as the falx cerebri and tentorium cerebelli; in the vertebral canal it forms a single tube ending at S2.
Overview
The cranial dura is made of dense collagen in two layers. The periosteal layer is firmly attached to the inner table of the skull, especially at the sutures and the skull base. The meningeal layer is continuous with the spinal dura through the foramen magnum and gives off four dural reflections:
• the falx cerebri in the longitudinal fissure;
• the tentorium cerebelli, a tent over the cerebellum whose free edge bounds the tentorial notch around the midbrain;
• the falx cerebelli;
• the diaphragma sellae roofing the pituitary fossa.
These partitions limit movement of the brain but also create the compartments across which brain tissue herniates. Along the attached edges of the falx and tentorium the layers enclose the superior and inferior sagittal, straight, transverse and sigmoid sinuses. The meningeal layer also forms sleeves around the cranial nerves as they leave, for example the optic nerve sheath.
The spinal dura is a single meningeal layer forming the dural sac. It is anchored above to the foramen magnum, ends at S2, and continues as the coccygeal ligament around the filum terminale. Lateral sleeves accompany each spinal nerve root to the intervertebral foramen. The epidural space between dura and vertebral canal contains fat and the valveless internal vertebral (Batson) venous plexus, which offers a route for metastasis.
The dura is richly innervated, which is why traction on it or on its vessels causes headache:
• supratentorial dura: CN V, including the tentorial branch of V1;
• posterior-fossa dura: C1–C3 and the vagus.
Its blood supply comes from the middle meningeal artery (from the maxillary artery through foramen spinosum), with smaller anterior and posterior meningeal branches.
- Location
Lines the cranial cavity and vertebral canal; outermost meninx.
Parts & subdivisions
- Periosteal (endosteal) layerInner periosteum of the skull; adherent at the sutures (limits epidural haematoma spread); absent in the vertebral canal.
- Meningeal layerContinuous with the spinal dura; forms the dural folds and nerve sheaths.
- Falx cerebriSickle-shaped fold in the longitudinal fissure between the hemispheres; encloses the superior (attached border) and inferior (free border) sagittal sinuses.
- Tentorium cerebelliSeparates the occipital lobes from the cerebellum; supratentorial vs infratentorial compartments; free margin forms the tentorial notch (incisura) for the midbrain.
- Falx cerebelli and diaphragma sellaeSmall fold between the cerebellar hemispheres; roof over the sella turcica pierced by the pituitary stalk.
- Spinal dural sacFrom the foramen magnum to S2; contains the cord, cauda equina and CSF; surrounded by the epidural space.
Anatomy
- Innervation
Supratentorial: meningeal branches of CN V (V1 tentorial nerve, V2, V3 via nervus spinosus). Infratentorial: C1–C3 and meningeal branches of the vagus and hypoglossal (C1 fibres). Pain from the dura is referred to the forehead (V1) or occiput (C2).
- Arterial supply
Middle meningeal artery (maxillary artery → foramen spinosum) supplies most of the cranial dura and calvarial bone; anterior meningeal (ethmoidal) and posterior meningeal (vertebral, occipital, ascending pharyngeal) branches.
Function
- Tough protective envelope for the brain and spinal cord
- Partitions the cranial cavity and limits brain displacement
- Encloses the dural venous sinuses
- Periosteum of the inner skull
Clinical significance
Epidural haematoma
A fracture through the thin pterion tears the middle meningeal artery. Arterial blood strips the periosteal dura off the bone but stops at the sutures, forming a biconvex collection. Rapid expansion leads to uncal herniation, so urgent craniotomy is required.
Post-dural-puncture headache
CSF leakage through a dural hole after LP or accidental puncture during epidural anaesthesia causes a postural headache: worse upright, relieved lying flat. The cause is sagging of the brain and traction on pain-sensitive structures. Atraumatic (pencil-point) needles reduce the risk, and an epidural blood patch treats persistent cases.
Test yourself
Where is CSF chiefly returned to the venous blood?
- Choroid plexus capillaries
- Internal vertebral venous plexus
- Ependymal cells of the central canal
- Arachnoid granulations into the dural venous sinuses
Answer: Arachnoid granulations into the dural venous sinuses
Arachnoid granulations, especially along the superior sagittal sinus, act as pressure-dependent, one-way valves into the dural venous sinuses. Some CSF also drains along cranial and spinal nerve sheaths to lymphatics. Scarring of the granulations after meningitis or SAH causes communicating hydrocephalus.
Compiled from standard anatomy and physiology references — see the Nervous System sources. For education only; not medical advice.