Umbilical cord
Funiculus umbilicalis
Also known as: umbilical arteries, umbilical vein, Wharton's jelly
The cord (≈50–60 cm at term) linking fetus and placenta, containing two umbilical arteries and one umbilical vein embedded in protective Wharton's jelly and covered by amnion.
Overview
The umbilical cord forms from the connecting stalk as the expanding amnion envelops the yolk-sac stalk and allantois. At term it is about 50–60 cm long and 1–2 cm thick, typically spirally twisted. It contains two umbilical arteries, branches of the fetal internal iliac arteries, which carry deoxygenated blood to the placenta, and one umbilical vein (the persisting left vein), which carries oxygenated, nutrient-rich blood back to the fetus — most of which bypasses the liver via the ductus venosus into the inferior vena cava. The vessels are cushioned in Wharton's jelly, a mucoid connective tissue rich in hyaluronan that resists compression and kinking. The cord lacks nerves; vessel tone is controlled locally.
After birth, the vessels constrict and close. Their remnants are: umbilical vein → ligamentum teres hepatis (round ligament of the liver); ductus venosus → ligamentum venosum; distal umbilical arteries → medial umbilical ligaments (proximal parts remain as the superior vesical arteries); and the allantois/urachus → median umbilical ligament.
- Location
From the fetal umbilicus to the fetal surface of the placenta (usually inserting near its centre).
Parts & subdivisions
- Umbilical arteries (2)Carry deoxygenated fetal blood to the placenta.
- Umbilical vein (1)Carries oxygenated blood to the fetus.
- Wharton's jellyMucoid connective tissue protecting the vessels; source of mesenchymal stem cells.
- Amniotic coveringOuter epithelium continuous with the amnion.
Function
- Conveys fetal blood to and from the placenta.
Clinical significance
Single umbilical artery
Found in ≈0.5–1 % of cords; associated with fetal renal and cardiac anomalies, aneuploidy and growth restriction — prompts a detailed anomaly scan.
Cord emergencies
Cord prolapse after membrane rupture (especially with malpresentation) compresses the vessels — an obstetric emergency requiring immediate delivery. Vasa praevia — unprotected fetal vessels (velamentous insertion) crossing the internal os — can rupture and exsanguinate the fetus.
Neonatal practice
Delayed cord clamping (≥1 min) improves infant iron stores; cord blood gases assess intrapartum hypoxia; the umbilical vein is used for emergency neonatal venous access; cord blood can be banked for haematopoietic stem cells.
Test yourself
How many vessels does the normal umbilical cord contain?
- One artery and one vein
- Two arteries and one vein
- One artery and two veins
- Two arteries and two veins
Answer: Two arteries and one vein
Two umbilical arteries carry deoxygenated blood from the fetus to the placenta; one umbilical vein returns oxygenated blood. A single umbilical artery is associated with renal and cardiac anomalies.
Compiled from standard anatomy and physiology references — see the Reproductive System sources. For education only; not medical advice.