Arrector pili muscle
Musculus arrector pili
Also known as: arrector pili, erector pili, pilomotor muscle, goose bumps, piloerection
The arrector pili is a small bundle of smooth muscle running from the papillary dermis to the bulge of a hair follicle; its sympathetic contraction erects the hair ("goose bumps") and squeezes sebum from the sebaceous gland.
Overview
Each arrector pili is a slender band of smooth muscle that runs obliquely from the connective tissue sheath of the hair follicle at the bulge region up to the papillary dermis. It lies on the side of the follicle that forms an obtuse angle with the skin surface, so the sebaceous gland sits in the angle between muscle and follicle.
Contraction, triggered by sympathetic adrenergic fibres in response to cold or fear, pulls the follicle upright and dimples the skin where the muscle attaches (cutis anserina, "goose flesh"). In furred mammals this traps an insulating layer of air or makes the animal look larger; in humans the thermal effect is negligible, but contraction compresses the sebaceous gland to express sebum. The muscle also anchors the bulge stem-cell niche, and sympathetic nerves wrapping it signal to the stem cells to regulate hair regeneration.
Anatomy
- Origin
Papillary layer of the dermis (just beneath the epidermis).
- Insertion
Connective tissue sheath of the hair follicle at the bulge, below the sebaceous gland.
- Action
Pulls the hair erect (piloerection), dimples the skin and compresses the sebaceous gland.
- Innervation
Sympathetic postganglionic adrenergic fibres (noradrenaline on α1-adrenoceptors).
- Histology
Bundles of spindle-shaped smooth muscle cells with central, elongated nuclei, eosinophilic cytoplasm; no striations.
Function
- Piloerection (goose bumps) in cold and emotional states
- Expression of sebum onto the hair and skin
- Structural anchor for the follicular stem-cell niche
Clinical significance
Piloerection as a clinical sign
Prominent goose flesh is a sign of opioid withdrawal (hence "cold turkey") and of sympathetic activation; it is absent in skin denervated by sympathetic lesions (e.g. Horner syndrome territory).
Piloleiomyoma
Benign tumour of arrector pili smooth muscle: firm, often painful red-brown papules; multiple lesions suggest hereditary leiomyomatosis and renal cell cancer (fumarate hydratase mutation).
Compiled from standard anatomy and physiology references — see the Integumentary System sources. For education only; not medical advice.